Boot the VM. It will start from the virtual floppy (Disk 1). You’ll see: Starting MS-DOS...
If you have original disks or want a custom image: ms dos 6.22 .img files -works with virtual box ...
Download SB16 (SoundBlaster 16) DOS drivers . Install them and set BLASTER=A220 I7 D1 H5 T4 in AUTOEXEC.BAT. Boot the VM
Set to (maximum). DOS cannot address more than 64MB without himem.sys issues, and 32MB is perfectly stable. or retro computing in general
If you're interested in learning more about MS-DOS 6.22, VirtualBox, or retro computing in general, here are some additional resources: